Causes And Forms Of Hemophilia
Hemophilia is an inherited disorder in blood and in such patients the blood does not clot. It is commonly seen males and females serves as carriers of this disease. Females will transmit the disease from father to grandson.
For normal blood clotting we require clotting factors and there are thirteen clotting factors in our blood. If any of these clotting factors are missing or is very low then the blood will not clot. In such cases the blood will continuously flow from the wounds. Further there are chances for internal bleeding too.
How Blood Clots
When ever the blood vessels get disturbed it results in bleeding. Our body then reacts to the bleeding by clotting the blood and thus protects us from losing the blood. For proper blood clotting, our body requires proteins which are called clotting factors.
The correct proportion of thirteen clotting factors allows the body to adhere the blood platelets at the bleeding spot and there by prevents the blood from oozing out. In hemophilic patients a slight jerk with in the joints may cause internal bleeding and the bleeding occurs with in the joints, muscles or soft tissues. It may cause inflammation and even at times cause mobility problems.
Types of Hemophilia
Hemophilia A
Hemophilia A is the most commonly found hemophilia and is also called classic hemophilia. In such patients the clotting factor VIII is found missing or found in very low concentration. Females are the carriers of this disease and a mother will transmit this disease to her son and in mother this gene won’t produce any symptoms. At the same time the son will show all symptoms.
Hemophilia B
Hemophilia B which is otherwise called Christmas disease. This type of hemophilia develops due to the deficiency or missing of the clotting factor IX. It is also seen normally in boys and the mothers will act as carriers
Hemophilia can also be classified in to severe, moderate and mild depending on the concentration of the clotting factors in the blood.
