Causes And Symptoms Of Pernicious Anemia
October 29, 2009
Anemia is a condition characterized by increased level of unhealthy red blood cell. These unhealthy blood cells have poor ability to absorb oxygen and carry it to different parts of the body.
Anemia can develop from several factors. Deficiency of vitamin B12 can cause anemia, which is also known as pernicious anemia. The red blood cells of people suffering from pernicious anemia are larger than normal blood cells. Moreover, the unhealthy blood cells are unable to multiply properly.
Pernicious anemia causes
Deficiency of vitamin B12 in the body is primarily responsible for developing pernicious anemia. Although, vitamin B12 deficiency can occur due to lack of this vitamin in the diet, overwhelming majority of pernicious anemia cases result from the body’s inability to absorb vitamin B12. If for some reason the parietal cells, present in the stomach lining, are destroyed, your body could not absorb vitamin B12.
The parietal cells produce intrinsic factor, a type of protein that helps the small intestine to absorb vitamin B12. Researchers have not yet identified the exact factors responsible for the destruction of the parietal cells. Stomach surgeries, involving removal of parts of the stomach, can increase the risk of parietal cells destruction. Sometimes genetic factors can cause loss of parietal cells.
Sometimes absence of vitamin B12 in the diet could trigger pernicious anemia. Aging can increase the risk of developing pernicious anemia. Sometimes alcoholism can lead to vitamin B12 deficiency. Celiac disease, Crohn’s disease and intestinal problems can also be responsible for pernicious anemia.
Prolonged consumption of diabetes medicines or drugs that reduce acid secretion in the stomach could cause pernicious anemia.
Symptoms of pernicious anemia
People suffering from pernicious anemia will experience fatigue and dizziness. The tongue becomes smooth and red. They might experience numbness and tingling in the hands and feet. If left untreated, an individual affected by pernicious anemia will experience nerve, brain and heart problems.
Pernicious anemia treatment
Vitamin B12 injections are usually prescribed for treating pernicious anemia. If pernicious anemia occurs due to vitamin B12 deficiency in the diet, it can be cured by increasing consumption of vitamin B12 rich foods and supplements.
Animal proteins, such as meat, egg, milk, fish and poultry are the richest sources of vitamin B12. Plant sources of vitamin B12 include whole grains, oranges, peas, beans, lentils, leafy green vegetables, sprouts, asparagus and broccoli.
Comments
Got something to say? Join the conversation and leave a comment below.