Parkinson’s Disease Risks and Prevention
August 7, 2009
Parkinson’s disease is a debilitating condition, which is characterized by destruction of the nerve cells in a particular region of the brain called the substantia nigra. The nerve cells or neurons present in substantia nigra are involved in the secretion of dopamine.
Dopamine is associated with communication between substantia nigra and corpus striatum. Smooth communication between these two parts of the brain is necessary for proper muscle movement. In Parkinson’s diseases, the damaged neurons of the substantia nigra inhibit secretion of dopamine. This impairs control over muscle functions and body movements.
Risk factors
The exact reasons for damage of neurons in the substantia nigra are not yet known. According to studies, Parkinson’s disease could be a hereditary condition. Presence of certain genetic abnormality might cause this condition. Researchers believe that environmental toxins might damage the neurons, causing Parkinson’s disease. Pesticides, carbon monoxide, manganese and carbon disulfide are particularly believed to be linked to the destruction of neurons. Increased oxidation of free radicals can damage neurons. Parkinson’s disease could be the side effect of certain medicines, which might reduce the dopamine level in the brain.
Parkinson’s disease symptoms
The risk of developing Parkinson’s disease increases after 60. However, sometimes Parkinson’s disease can occur in the 50s. Tremors at rest, rigidity or muscle stiffness, slowness in movement and Parkinson gait are the symptoms of Parkinson’s disease. Parkinson gait is unsteady walking gesture associated with Parkinson’s disease.
Parkinson’s disease prevention
It is seen that the symptoms of Parkinson’s disease start appearing only after 60 to 80 percent neurons had been damaged. This makes it extremely difficult to treat the disease.
Besides, medication, Parkinson’s disease is sometimes treated by surgically implanting devices, which could reduce muscle tremors. Studies have found evidence that people who eat Mediterranean diet are less likely to develop Parkinson’s disease.
Increasing intake of fiber rich food and antioxidant rich fruits and vegetables could prevent Parkinson’s disease. Omega-3 fatty acids present in fish oil, nuts, whole grains, bran, flax seed, canola oil, soy oil and green leafy vegetables could prevent destruction of neurons.
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